Reference #: 1010329
SHIFT:Day (United States of America)Seeking Breakthrough MakersChildren's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.CHOP's Commitment to Diversity, Equity, and InclusionCHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.A Brief Overview
The Research Assistant will work with the Principal Investigators, Research Lab Director, Research Scientists, Post-Doctoral Fellows, Research Assistants, Senior Research Technicians, Graduate Students, and other laboratory staff. Importantly, the Research Technician will be part of an established "in vivo team" that collaboratively conducts studies and provides coverage for each other as necessary. The Research Assistant must document all required preclinical testing studies of novel molecularly targeted agents in laboratory mouse models bearing Patient-Derived Xenografts or Allografts as part of ThePediatric PreclinicalIn VivoTesting (PIVOT) consortium (https://preclinicalpivot.org/) and other NIH funded activities.S/he must be able to and willing to learn/perfect standard techniques as well as:
Take responsibility for conducting a set of Pediatric PreclinicalIn VivoTesting (PIVOT) Consortium mouse trials in a state-of-the-art rodent barrier facility with an ability to maintain the "clean" or specific Pathogen Free (SPF) environment (under supervision of Principal Investigators, Lab Director and with the help of Research Assistants and senior laboratory staff). Have experience with handling mice and willingness to learn mouse model experiments consisting of survival surgery tumor implantation procedures, subcutaneous injections, oral gavage, intraperitoneal injections, intravenous tail vein injections, blood collections, tumor tissue and organ collections, etc. Work independently on mouse irradiation studies after initial training in procedures and equipment. Carefully maintain, passage and re-stock the patient-derived xenografts used to perform most of the in vivo work. Maintain cage cards, animal histories, and other records as required. Carefully follow laboratory safety procedures and perform experiments in compliance with research safety standards. Practice safety, environmental, and/or infection control methods Complete assigned training on standard operating procedures pertaining to job functions. Perform miscellaneous job-related duties as assigned.A successful applicant will be able to work independently after the initial training and be self-directed while providing help to more junior lab personnel. It will be required to consistently exercise discretion and judgment in the execution and interpretation of experiments, and data analysis.What you will do
Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee
Performs research procedures on experimental samples as directed
Records and checks experiments/ results for completeness and accuracy
Performs calculations and maintains appropriate log and lab notebooks
Performs tasks that require familiarity with fundamental techniques and lab equipment
May assist with planning specific research pro ocols and procedures
Maintains office, lab area, solutions, reagents, supplies and equipment, disposes of specimens, media and other materials (using appropriate procedures)
Assists in care and maintenance of lab equipment
May coordinate schedules of tests and procedures
Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
Records results, organizes data and maintains lab notebook in an organized manner
Compiles and helps analyze data, prepares charts, graphs, and results of studies as directed
Conducts literary searches as directed
Education Qualifications
High School Diploma / GED Required
Associate's Degree Preferred
Bachelor's Degree Preferred
Experience Qualifications
At least one (1) year of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Required
At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred
Skills and Abilities
Intermediate understanding of lab procedures, protocols, and equipment.
Basic exposure to lab specific experiments / techniques and scientific analysis
Excellent verbal and written communications skills
Excellent organizational skills
Solid critical thinking / problem-solving skills
Solid analytical skillsTo carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine. Learn more.Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.EEO / VEVRAA Federal Contractor | Tobacco StatementChildren's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.