Reference #: REQ0000064706
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The Department of Pediatric Hematology/Oncology at Penn State Hershey College of Medicine, in Hershey, PA, is currently accepting applications for a postdoctoral scholar. The lab focuses on delineating the epigenetic pathways that regulate normal hematopoiesis and to further determine how regulatory networks are perturbed in leukemia. Our current research focuses are: 1) Investigating the underlying molecular mechanisms by which 3D genome topology controls the hematopoietic transcription program and lineage differentiation in normal and malignant hematopoiesis. 2) Delineating the role of long noncoding RNAs in regulating CTCF boundary function during hematopoiesis and leukemogenesis. 3) Epigenetic and transcriptional regulation of hematopoietic stem cell function. We utilize a variety of approaches including biochemical, proteomic, genomic, genome editing, and mouse modeling to study these questions. Here are representative recent publications from the lab (Luo et al., Blood, 2018, 132 (8): 837-848; Luo et al., 2019, Cancer Cell, 36: 645-659; Zeisig et al., Science Translational Medicine, 2021, 13 (482): eabc4822; Zhu et al., Nature Communications, 2021, 12 (1): 1956. Doi: 10.1038/s41467-021-22095-2); Li et al., 2020. NAR, 48(6): 3119-3133.Candidates should have obtained a PhD or an MD/PhD degree in the fields of molecular biology, biochemistry, bioinformatics, mouse genetics or a related field. The candidate should have evidence of prior productive scientific work in the form of publications in peer-reviewed journals.This is a limited-term appointment funded for one year from date of hire.Prior experience in the study of gene regulation, hematopoiesis, and/or use of mouse models is preferred. Interested candidates should upload their Curriculum Vitae and a cover letter describing their background and research interests in the application and additionally send to [email protected] will require successful completion of background check(s) in accordance withUniversitypolices.The Pennsylvania State University is committed to and accountable for advancing diversity, equity, and inclusion inall ofits forms.We embrace individual uniqueness, foster a culture of inclusive excellence that supports both broad and specific diversity initiatives, leverage the educational and institutional benefits of diversity, and engage all individuals to help them thrive. We value inclusive excellence as a core strength and an essential element of our public service mission.CAMPUS SECURITY CRIME STATISTICS:Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act and the Pennsylvania Act of 1988, Penn State publishes a combined Annual Security and Annual Fire Safety Report (ASR). The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters. The ASR is available for review here.Employment with the University will require successful completion of background check(s) in accordance with University policies.EEO IS THE LAWFederal Contractors Labor Law Poster
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Hershey, PAPenn State is an equal opportunity, affirmative action employer, and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If you are unable to use our online application process due to an impairment or disability, please contact 814-865-1473.