Upstream Development Engineer

The Upstream development engineer will work in the upstream process development team to design, execute, and optimize consistent fed-batch cell culture processes to produce quality recombinant proteins through laboratory studies. As part of the team, they will ensure that these processes are predictable, scalable, and controlled using multiple sizes of bioreactors (ambr15, ambr250, and bench-top scale bioreactors). The position will support tech transfer of developed and locked cell culture processes to the pilot team and CMOs. Roles and Responsibilities:Conduct upstream process unit operations, which include cell banking, cell expansion, bioreactor process, optimization, and characterization.Work collaboratively within the department as well as cross-functional peers to execute various upstream studies using shake flasks, wave bioreactors, and benchtop bioreactors.Use high throughput tools such as AMBR15, AMBR25,0, and Robocolumns as well as analytical tools like cell counters, bioanalyzers to support studies.Coordinate with the testing team to submit a large number of study samples, compiling results received, analyzing data using data analysis tools such as Microsoft Excel, JMP, Spotfire etc., as well as summarizing the findings.Document experiments using an electronic lab notebook, in addition to supporting technical reports for studies.