Bioprocess Analytical Associate

The position will support a client team that is responsible for developing robust processes for cell lines producing protein therapeutics. These are proteins that are chosen by research units as the candidate molecules for the treatment of various medical conditions spread across oncology, neuroscience, inflammation, and many others. The processes developed by the client group are used in GMP manufacturing facilities to produce the molecules in large quantities for clinical and commercial needs. Almost all the molecules currently produced employ Chinese hamster ovary (CHO) cells as the host cells.One of the vital components of process development is controlling the metabolism of the cells in culture. CHO cells consume large amounts of nutrients, including amino acids and other metabolites, to produce molecules of interest as well as other byproducts. Quantification of amino acids in the culture medium, protein concentration, as well as several other metabolites and byproducts, is key to building robust processes and ensuring product quality. The successful candidate will drive the analytical support to the team by performing analytical tests on culture samples.Job Responsibilities and Requirements:The successful candidate will drive the analytical support to the client group. The candidate will coordinate with the team to receive and manage samples, perform analytical tests, process the data, and provide it back to the scientists.The candidate is expected to have basic skills in biotechnology and analytical chemistry.Perform various analytical, cell culture, and molecular biology techniques, including but not limited to amino acid analysis using UPLC and titer assay using HPLC.Perform data analysis using Empower and Microsoft Excel and compose scientific documents for electronic lab notebooks.