Assistant Project Scientist Apply now to Assistant Project Scientist Job #JPF10225
Neurology / David Geffen School Of Medicin / UCLA
Position overview Position title: Project Scientist
Salary range: 104,000 to 195,000
Review timeline: every 3 years from initial appt
Application Window
Open date: March 11, 2025
Next review date: Monday, Mar 31, 2025 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Friday, Apr 11, 2025 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
Applications are sought for a full-time Assistant Project Scientist position in the Samelson Lab. The successful candidate will combine extensive chemoproteomics experience, protein expression, mammalian tissue culture, spectroscopy, and bioinformatics skills to understand iron and iron-chaperone distribution, function, and disease-relevance in human cell culture models of neurodegenerative diseases. The Samelson Lab is looking to understand how metals, especially those related to electron transport or iron homeostasis, affect disease-relevant phenotypes, such as protein aggregation, mitochondrial dysfunction, DNA damage, and lysosomal dysfunction. We are looking to combine mass-spectrometry-based methods for assessing iron occupancy in vivo with proteome-wide iron-chaperone interactome maps and genetic modifiers of these processes using CRISPR-screening.The ideal candidate will have extensive experience in cell and molecular biology, bioinformatics, metal-binding studies, mass spectrometry, and confocal microscopy. The candidate should have a strong team mindset to work collaboratively with geneticists, biochemists, and chemical biologists to design, implement, improve, and analyze experiments.A successful candidate(s) will have the following qualifications: PhD in Chemistry or Biochemistry related discipline At least 4 years post graduate fellowship or experience Ability to work in a collaborative interdisciplinary environment and experience in establishing new methods and approaches Deep knowledge and willingness to teach others about the role of metals in human cells Experience generating and analyzing mass spectrometry data, especially protein-protein interactions and metal occupancy sites. Experience with analysis of protein-metal binding both in vitro and in vivo Experience analyzing large protein-protein interaction datasets Experience with sequencing, cloning, cell culture, DNA/RNA/Protein purification Experience with standard molecular and epigenetic methods Prefer experience studying heavy metal (especially iron) biology and an interest in neurodegenerationDocument requirementsCurriculum Vitae - Your most recently updated C.V.3-6 referencesBibliographyStatement of Research Statement on Contributions to Equity, Diversity, and InclusionCover Letter (Optional)Application procedure: Apply by submitting your application to our online RECRUIT system at https://recruit.apo.ucla.edu/.JPF10225 Screening of applicants will begin immediately and will continue until the position is filled. The posted UC salary scales set the minimum pay determined by rank and step at appointment. See https://www.ucop.edu/academic-personnel-programs/files/2024-25/july-2024-scales/t37-b.pdf The salary range for this position is $104,000 to $195,000.The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star.The David Geffen School of Medicine Anti-racism roadmap is our co-created path to ensuring racial justice, equity, diversity and inclusion. We are committed to actively dismantling structural racism in our organization as described in more detail at: https://medschool.ucla.edu/diversity-anti-racism-roadmapAll aspects of searches are confidential and all candidates are expected to review and abide by UC Regents Policy 1111 on Statement on Ethical Values and Standards of Conduct https://regents.universityofcalifornia.edu/governance/policies/1111.html. The University of California is committed to creating and maintaining a community dedicated tothe advancement, application, and transmission of knowledge and creative endeavors throughacademic excellence, where all individuals who participate in University programs and activitiescan work and learn together in a safe and secure environment, free of violence, harassment, bullying and other demeaning behavior, discrimination, exploitation, or intimidation. With thiscommitment as well as a commitment to addressing all forms of academic misconduct, UCLA conducts targeted employment reference checks for finalists to whom departments or other hiring units would like to extend formal offers of appointment into Academic Senate faculty positions. The targeted employment reference checks involve contacting the finalists’ current and prior places of employment to ask whether there have been substantiated findings of misconduct that would violate the University’s Faculty Code of Conduct. To implement this process, UCLA requires all applicants for Academic Senate faculty positions to complete, sign, and upload the form entitled “Authorization to Release Information” into RECRUIT as part of their application. If the applicant does not include the signed authorization to release information with the application materials, the application will be considered incomplete. As with any incomplete application, the application will not receive further consideration. Although all applicants for faculty recruitments must complete the entire application, only finalists (i.e., those to whom the department or other hiring unit would like to extend a formal offer) considered for Academic Senate faculty positions will be subject to targeted employment reference checks.Qualifications Basic qualifications Ph.D. + 4Y post graduate experienceAdditional qualifications Experience with mass spectrometry especially related to iron and copper in cells Experience with bioinformatics tools for analyzing mass spectrometry data Familiarity with acquiring mass spectrometry data, especially as related to metals Experience working with publicly available databases and repositories Excellent oral and written communication skills Experience integrating AI-based protein structure prediction with chemoproteomics datasets Preferred qualifications First-author publication in relevant field Experience in the biology of heavy metals Experience in proteomicsApplication Requirements Document requirements
Curriculum Vitae - Your most recently updated C.V.
Cover Letter (Optional)
Statement of Research (Optional)
Statement of Teaching (Optional)
Statement on Contributions to Equity, Diversity, and Inclusion - An EDI Statement describes a faculty candidate’s past, present, and future (planned) contributions to equity, diversity, and inclusion. To learn more about how UCLA thinks about contributions to equity, diversity, and inclusion, please review our EDI Statement FAQ document, and Sample EDI Statements.
(Optional)
Reference check authorization release form - Complete and upload the reference check authorization release form
Misc / Additional (Optional)
Reference requirements
3-5 required (contact information only)
Only references of serious candidates will be contactedApply link: https://recruit.apo.ucla.edu/JPF10225 Help contact: jshinn@mednet.ucla.eduAbout UCLA As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the University of California’s Affirmative Action Policy, please visit https://www.ucop.edu/academic-personnel-programs/files/apm/apm-035.pdf.For the University of California’s Anti-Discrimination Policy, please visit https://policy.ucop.edu/doc/1001004/Anti-Discrimination.As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.
“Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
UC Sexual Violence and Sexual Harassment Policy (https://policy.ucop.edu/doc/4000385/SVSH)
UC Anti-Discrimination Policy for Employees, Students and Third Parties
APM - 035: Affirmative Action and Nondiscrimination in Employment (https://www.ucop.edu/academic-personnel-programs/files/apm/apm-035.pdf)
Job location
Los Angeles, CA